Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report.
Identifieur interne : 000E04 ( PubMed/Checkpoint ); précédent : 000E03; suivant : 000E05Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report.
Auteurs : Kunaal Dhingra [Inde] ; Shobha PrakashSource :
- Gerodontology [ 1741-2358 ] ; 2012.
Descripteurs français
- KwdFr :
- Acide valproïque (usage thérapeutique), Adulte d'âge moyen, Anticonvulsivants (effets indésirables), Anticonvulsivants (usage thérapeutique), Croissance exagérée de la gencive (), Extraction dentaire, Femelle, Gencive (), Gingivectomie, Grand mal épileptique (traitement médicamenteux), Humains, Hyperplasie gingivale (), Mobilité dentaire (), Mâchoire partiellement édentée (), Phénobarbital (effets indésirables), Phénytoïne (effets indésirables), Prothèse dentaire complète, Études de suivi.
- MESH :
- effets indésirables : Anticonvulsivants, Phénobarbital, Phénytoïne.
- traitement médicamenteux : Grand mal épileptique.
- usage thérapeutique : Acide valproïque, Anticonvulsivants.
- Adulte d'âge moyen, Croissance exagérée de la gencive, Extraction dentaire, Femelle, Gencive, Gingivectomie, Humains, Hyperplasie gingivale, Mobilité dentaire, Mâchoire partiellement édentée, Prothèse dentaire complète, Études de suivi.
English descriptors
- KwdEn :
- Anticonvulsants (adverse effects), Anticonvulsants (therapeutic use), Denture, Complete, Epilepsy, Tonic-Clonic (drug therapy), Female, Follow-Up Studies, Gingiva (drug effects), Gingival Hyperplasia (chemically induced), Gingival Overgrowth (chemically induced), Gingivectomy, Humans, Jaw, Edentulous, Partially (complications), Middle Aged, Phenobarbital (adverse effects), Phenytoin (adverse effects), Tooth Extraction, Tooth Mobility (chemically induced), Valproic Acid (therapeutic use).
- MESH :
- chemical , adverse effects : Anticonvulsants, Phenobarbital, Phenytoin.
- chemical , therapeutic use : Anticonvulsants, Valproic Acid.
- chemically induced : Gingival Hyperplasia, Gingival Overgrowth, Tooth Mobility.
- complications : Jaw, Edentulous, Partially.
- drug effects : Gingiva.
- drug therapy : Epilepsy, Tonic-Clonic.
- Denture, Complete, Female, Follow-Up Studies, Gingivectomy, Humans, Middle Aged, Tooth Extraction.
Abstract
Drug-influenced gingival overgrowth is an unaesthetic overgrowth of gingiva principally associated with intake of drugs like phenytoin, cyclosporin A and nifedipine. Its occurrence in both dentate and edentulous regions of oral cavity is poorly understood.
DOI: 10.1111/j.1741-2358.2012.00624.x
PubMed: 22612838
Affiliations:
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pubmed:22612838Le document en format XML
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<affiliation wicri:level="1"><nlm:affiliation>Department of Periodontics, NSVK Sri Venkateshwara Dental College, Bangalore, Karnataka, India. kunaaldhingra@yahoo.co.in</nlm:affiliation>
<country xml:lang="fr">Inde</country>
<wicri:regionArea>Department of Periodontics, NSVK Sri Venkateshwara Dental College, Bangalore, Karnataka</wicri:regionArea>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anticonvulsants (adverse effects)</term>
<term>Anticonvulsants (therapeutic use)</term>
<term>Denture, Complete</term>
<term>Epilepsy, Tonic-Clonic (drug therapy)</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Gingiva (drug effects)</term>
<term>Gingival Hyperplasia (chemically induced)</term>
<term>Gingival Overgrowth (chemically induced)</term>
<term>Gingivectomy</term>
<term>Humans</term>
<term>Jaw, Edentulous, Partially (complications)</term>
<term>Middle Aged</term>
<term>Phenobarbital (adverse effects)</term>
<term>Phenytoin (adverse effects)</term>
<term>Tooth Extraction</term>
<term>Tooth Mobility (chemically induced)</term>
<term>Valproic Acid (therapeutic use)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Acide valproïque (usage thérapeutique)</term>
<term>Adulte d'âge moyen</term>
<term>Anticonvulsivants (effets indésirables)</term>
<term>Anticonvulsivants (usage thérapeutique)</term>
<term>Croissance exagérée de la gencive ()</term>
<term>Extraction dentaire</term>
<term>Femelle</term>
<term>Gencive ()</term>
<term>Gingivectomie</term>
<term>Grand mal épileptique (traitement médicamenteux)</term>
<term>Humains</term>
<term>Hyperplasie gingivale ()</term>
<term>Mobilité dentaire ()</term>
<term>Mâchoire partiellement édentée ()</term>
<term>Phénobarbital (effets indésirables)</term>
<term>Phénytoïne (effets indésirables)</term>
<term>Prothèse dentaire complète</term>
<term>Études de suivi</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Anticonvulsants</term>
<term>Phenobarbital</term>
<term>Phenytoin</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anticonvulsants</term>
<term>Valproic Acid</term>
</keywords>
<keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Gingival Hyperplasia</term>
<term>Gingival Overgrowth</term>
<term>Tooth Mobility</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Jaw, Edentulous, Partially</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Gingiva</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Epilepsy, Tonic-Clonic</term>
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<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Anticonvulsivants</term>
<term>Phénobarbital</term>
<term>Phénytoïne</term>
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<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Grand mal épileptique</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Acide valproïque</term>
<term>Anticonvulsivants</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Denture, Complete</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Gingivectomy</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Tooth Extraction</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Croissance exagérée de la gencive</term>
<term>Extraction dentaire</term>
<term>Femelle</term>
<term>Gencive</term>
<term>Gingivectomie</term>
<term>Humains</term>
<term>Hyperplasie gingivale</term>
<term>Mobilité dentaire</term>
<term>Mâchoire partiellement édentée</term>
<term>Prothèse dentaire complète</term>
<term>Études de suivi</term>
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<front><div type="abstract" xml:lang="en">Drug-influenced gingival overgrowth is an unaesthetic overgrowth of gingiva principally associated with intake of drugs like phenytoin, cyclosporin A and nifedipine. Its occurrence in both dentate and edentulous regions of oral cavity is poorly understood.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22612838</PMID>
<DateCompleted><Year>2012</Year>
<Month>12</Month>
<Day>21</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1741-2358</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>29</Volume>
<Issue>2</Issue>
<PubDate><Year>2012</Year>
<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>Gerodontology</Title>
<ISOAbbreviation>Gerodontology</ISOAbbreviation>
</Journal>
<ArticleTitle>Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report.</ArticleTitle>
<Pagination><MedlinePgn>e1201-6</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1111/j.1741-2358.2012.00624.x</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Drug-influenced gingival overgrowth is an unaesthetic overgrowth of gingiva principally associated with intake of drugs like phenytoin, cyclosporin A and nifedipine. Its occurrence in both dentate and edentulous regions of oral cavity is poorly understood.</AbstractText>
<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">This report highlights clinical and histological description, aetiology and management of gingival overgrowth in a partially edentulous (non-denture wearer) 60-year-old female patient with epilepsy on phenytoin and phenobarbital drugs from past 7 years.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">Patient's intraoral examination revealed lobulated and fibrotic consistency gingival overgrowth around teeth and on partially edentulous ridges of upper and lower arches along with generalised tooth mobility. Under medical consultation, full mouth extraction, surgical excision of overgrowth followed by complete denture rehabilitation and replacement of combination drugs with sodium valproate were accomplished.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Histologically, the lesion showed fibro-epithelial hyperplasia. Clinical results after 6 months demonstrated almost complete resolution of gingival overgrowth.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The findings of present case suggest that gingival overgrowth can occur even in partially edentulous ridges (not exposed to denture wear) that could be due to persistence of gingival overgrowth, which may not resolve completely following tooth extraction or occurs because of incorporation of specific subpopulation of gingival fibroblasts in alveolar ridge mucosa.</AbstractText>
<CopyrightInformation>© 2012 The Gerodontology Society and John Wiley & Sons A/S.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Dhingra</LastName>
<ForeName>Kunaal</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Department of Periodontics, NSVK Sri Venkateshwara Dental College, Bangalore, Karnataka, India. kunaaldhingra@yahoo.co.in</Affiliation>
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<Author ValidYN="Y"><LastName>Prakash</LastName>
<ForeName>Shobha</ForeName>
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<MeshHeading><DescriptorName UI="D007576" MajorTopicYN="N">Jaw, Edentulous, Partially</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
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<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D010634" MajorTopicYN="N">Phenobarbital</DescriptorName>
<QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName>
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<QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName>
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<MeshHeading><DescriptorName UI="D014081" MajorTopicYN="N">Tooth Extraction</DescriptorName>
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<MeshHeading><DescriptorName UI="D014086" MajorTopicYN="N">Tooth Mobility</DescriptorName>
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